Regulate hormone and nerve function, reduce menopause symptoms.
Suggested use: 1 capsule/time, twice per day.
Main ingredients: Red clover, Chaste Berry, Black cohosh.
Recommend for: Women with hot flash, night sweating, anxiety and depress.
Caution: Not recommend for patients with breast cancer or heavy manstration.
Red clover, chaste berry, and black cohosh are commonly used folk herbs in Europe and America. They are the three herbs screened out in the UIC/NIH Center for Botanical Dietary Supplement Research in Women's Health when Dr. Liu were in Illinois State University Chicago. Both red clover and chaste berry contain phytoestrogens that can bind to estrogen receptor and regulate the gene expression of estrogen and progesterone receptors, thus are used for hot flash and night sweats of menopause women. Black cohosh can act on serotonin receptors, thereby regulating function of the nervous system and improving symptoms such as anxiety and depression. Unlike the synthetic estrogens, there is no research report on phytoestrogens causing breast cancer or heart disease yet so far.
1. Liu, JH et al. Evaluation of estrogenic activities of plant extracts on the potential treatment of menopausal sympotoms. Journal of Agricultural and Food Chemistry 2001; 49 (5), 2472-2479
2. Liu, JH et al Isolation of linoleic acid as an estrogenic compound from the fruits of Vitex agnus-castus L. (chaste berry). Phytochemistry 2004;11 (1), 18-23
3. Burdette, J et al. Trifolium pratense (red clover) exhibits estrogenic effects in vivo in ovariectomized Sprague-Dawley rats. J. Nutr. 2002;132(1):27-30
4. Burdette, J et al. Black cohosh acts as a mixed competitive ligand and partial agonist of the serotonin receptor. Journal of Agricultural and Food Chemistry 2003;51 (19), 5661-5670
5. Burdette, J et al. Black cohosh (CIMICIFUGA RACEMOSA L.) protects against menadione-induced DNA damage through scavenging of reactive oxygen species: Bioassay-Directed isolation and characterization of Active principles. Journal of Agricultural and Food Chemistry 2003; 50 (24), 7022-8
6. Wuttke W et al. The non-estrogenic alternative for the treatment of climacteric complaints: black cohosh (Cimicifuga or Actaea Racemosa). J Steroid Biochem Mol Biol 2014;139:302-10.